Endoplasmic reticulum stress and intestinal inflammation
نویسندگان
چکیده
منابع مشابه
Endoplasmic reticulum stress and inflammation.
Endoplasmic reticulum (ER) stress due to the presence of misfolded or unfolded proteins in the ER invokes a fundamental biological response, termed the unfolded protein response (UPR). The UPR is orchestrated by three main proximal effectors, of which the IRE1/XBP1 pathway represents the evolutionarily most conserved one. Due to its high secretory burden, the intestinal epithelium is highly sus...
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ژورنال
عنوان ژورنال: Mucosal Immunology
سال: 2009
ISSN: 1933-0219,1935-3456
DOI: 10.1038/mi.2009.122